A Secret Weapon For ceesdekker.net
A Secret Weapon For ceesdekker.net
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Nanotechnology gives A selection of alternatives to add to biology. Here I will present examples exactly where nanofabrication – the chance to make confined constructions with dimensions at will – is utilised to look at the biophysics of solitary molecules and cells. I'll current some examples from our lab:
Our team scientific studies bacterial mobile division and it is aiming to represent a ‘base up biology’ in synthetic cells that could autonomously divide. Our primary fascination lies in mobile division, chromatin construction, and spatial Management.
, Groningen researchers present the outcomes of their attempts to generate labs additional sustainable and supply tricks for other labs.
Regretably, For a long time after Iijima’s report, the manufacture of clean nanotubes was cumbersome. In 1996, even so, the group of Richard Smalley at Rice University managed to generate solitary-walled carbon nanotubes at superior yield. Soon after, I contacted Smalley, and we chose to sign up for forces to measure the transportation through a single carbon nanotube.
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Direct immobilization of indigenous yeast iso-1 cytochrome c on bare gold: speedy electron relay to redox enzymes and zeptomole protein-film voltammetry
Considering that 2000 he moved to single-molecule biophysics and nanobiology, with research from DNA supercoiling experiments of nucleosomes and DNA repair service proteins to DNA translocation by way of nanopores. Not too long ago his study has centered on learning cell division with micro organism on chip, although his greatest desire is from the route of realizing artificial cells.
2000, discovery that nanotubes can carry amazing significant present densities; solved the controversial problem of Digital transportation through DNA molecules by measurements of insulating conduct at The only molecule amount; and demonstration of the AFM method for solitary-molecule manipulation of nanotubes
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Resolving the move sizing in condensin-pushed DNA loop extrusion identifies ATP binding as being the action-making approach
‘The concept You can find such a point being a commencing, a major bang, is already an interesting signpost to contemplate that there was a creator. But additional frequently, and on cees dekker The premise of pure rationality, I also get there in a Christian interpretation of truth. An atheistic worldview is a naturalistic worldview: fundamentally, you'll find only atoms and normal forces that we could evaluate.
2001, discovery of one-electron transistors at place temperature dependant on nanotubes; realization of to start with logic circuits with carbon nanotube equipment; and discovery of the molecular structure of DNA repair enzymes with AFM
Enable’s to start with search again at this time when you made a decision to change your aim from superconductivity and nanotubes to biology at the conclusion of the 1990s.
2004, discovery of new physics in translocation of DNA through nanopores; 1st experimental research of ions conduction in nanofluidic channels; first electrochemistry with particular person single-wall carbon nanotubes; STM detection and Charge of phonons in carbon nanotubes; very first electrical docking of microtubules on kinesin-coated nanostructures; first biophysics characterization on the mechanical Qualities of double-stranded RNA; and initially single-molecule analyze of DNA translocation by a restriction-modification enzyme.